- Isolation and charactrization of pectin from sum agro-industrial Wastes
journal of enviromental sciences , 2011 Vol 40 NO.2 239-249, الصفحات 10, jan 2011
أ.د. محمد صفوت عطا عبد المعز عفيفى
أ.د. صالح حسن صالح الشرقاوى
أ.د. منى جوده محمد زغلول
ولاء كامل معاطى محمد موسى
الملخص الملخص Isolation and charactrization of pectin from sum agro-industrial Wastes Isolation and charactrization of pectin from sum agro-industrial Wastes
- Phytochemical and Biological Studies of Nico-tiana glauca R. Grah. Leaves
الصفحات 103-111
أ.د. صالح حسن صالح الشرقاوى
أ.د. منى جوده محمد زغلول
Marzouk A. M.
باهر علاء الدين ابو زاهر ابراهيم
الملخص الملخص Phytochemical and Biological Studies of Nico-tiana glauca R. Grah. Leaves Phytochemical study of Nicotiana glauca R. Grah. leaves resulted in the isolation of 9 compounds. Two of them were isolated for the first time as natural compounds; 3-methylthioindole and indole-3-thiol. Another two compounds were isolated for the first time from the genus. Indole-3-carbaldehyde and docosanol and Scopoletin were isolated from the species for the first time. The rest of nine compounds are previously isolated from the plant; rutin, ?-sitosterol, nicotine and anabasine. The chemical identity of the isolated compounds was established based on the different spectroscopic techniques. The different extracts showed good antioxidant, moderate anticancer in EAC assay and weak antibacterial activities.
- Biodegradation of Nicotine by Streptomyces Griseus Atcc 13273 and Other Microbial Systems
Journal of Environmental Sciences, الصفحات 171-178
أ.د. صالح حسن صالح الشرقاوى
Marzouk A. M.
باهر علاء الدين ابو زاهر ابراهيم
أ.د. منى جوده محمد زغلول
الملخص الملخص Biodegradation of Nicotine by Streptomyces Griseus Atcc 13273 and Other Microbial Systems Screening Studies have shown anumber of microgranisms capable of transforming nicotine, 3-(1-methylpyrrolidin-2-yl)pyridine. scale-up fermentation with streptomyces griseus ATCC 13273, resulted in the ptoduction N-(4,4-dimethyl-2-oxobut-4-yl) acetamide and4-amino-4-dimethyl-but-2-one in1.8% and 1% yield respectively while Absidia pseudocylinderospora ATCC 24169and co-mamonas testosteroni ATCC 11996 degrade nicotine copletely. the stucdure of metabolites was confirmed by different spectroscopic techniques.
- Chemical Study of Myoporum laetum Forst. F
Mansoura Journal of Pharmaceutical Sciences, الصفحات 73-86, 2003
M.-F. Lahloub
أ.د. صالح حسن صالح الشرقاوى
د. ممدوح منصور احمد على
د. أمل عبد الحميد حسن جلاله
- Phytochemical investigation of unused parts of Hibiscus sabdariffa
Journal of American sciences, الصفحات 29-35, 2012
AMER M.M.A.
أ.د. صالح حسن صالح الشرقاوى
F. M. Abdel Bar
A.A.Ashour
الملخص الملخص Phytochemical investigation of unused parts of Hibiscus sabdariffa Abstract: Twelve compounds have been isolated from the unused parts of Hibiscus sabdariffa. The isolated compounds were identified as oleic acid (1), β-sitosterol (2), lupeol (3), oleanolic acid (4), betulinic acid (5), 5α, 8αEpidioxyergosta-6,22-dien-3β-ol (6), 5’-Methoxy Propacin (7) Aquillochin (8), β-sitosterol glucoside (9), 5,8dihydroxy dodeca-5,7-dienedioic acid (10), gallic acid (11) and kaempferol 3-O-(6-O-trans-p-coumaroyl)-β-Dglucopyranoside (trans tiliroside) (12). The chemical identity of these compounds was elucidated based on spectroscopic data (NMR, UV, MS and IR spectra). This is the first report to indicate isolation of these compounds from H. Sabdariffa (except β-sitosterol). Compounds 7, 8, 11 and 12 displayed a remarkable antioxidant activity compared to ascorbic acid.
- Macro-arid Micromorphology of Schinus Terebinthifolius Radd. Growing in Egypt
Part III. The Fruits and Seeds
جامعة المنصورة - كلية الصيدلة, الصفحات 171-184
أ.د. محمد صفوت عطا عبد المعز عفيفى
أ.د. احمد فؤاد احمد ابراهيم حليم
أ.د. صالح حسن صالح الشرقاوى
سعد الدين كراوية - جامعة المنصورة - كلية الصيدلة - العقاقير
الملخص الملخص Macro-arid Micromorphology of Schinus Terebinthifolius Radd. Growing in Egypt
Part III. The Fruits and Seeds The macro- and micromorphological characters of the fruits and seeds of Schinus terebinthifolius Radd.(Family:Ana cardiaceae) are presented
- BIOTRANSFORMATION OF cx-SANTONIN
جامعة المنصورة - كلية الصيدلة, الصفحات 99-109
أ.د. صالح حسن صالح الشرقاوى
أ.د. أحمد محمد محمد خليل زغلول
Farid A. Badria
أ.د. جلال طه معتوق عبد الحى
الملخص الملخص BIOTRANSFORMATION OF cx-SANTONIN Bacillus cereus U1-1477 was able to convert a-santonin into 1,2-dihydrosantonin in a 64% yield. The chemical identity of the obtained metabolite was confirmed by UV, IR, 1D- and 2D-, 1H-, 13c-NMR spectroscopy. Biological evaluation showed a complete loss of both anthelmentic and antimicrobial activity of 1,2- dihydrosantonin in comparison to a-santonin.
- Preliminary Screening of Malaysian Plants for Antimicrobial Activity
جامعة المنصورة - كلية الصيدلة, الصفحات 87-98
أ.د. صالح حسن صالح الشرقاوى
عبد المناف على - جامعة بريتانيا - كلية الصيدلة- قسم البيوتكنولوجى
محيى الدين داهان - جامعة بريتانيا - كلية الصيدلة- قسم البيوتكنولوجى
الملخص الملخص Preliminary Screening of Malaysian Plants for Antimicrobial Activity ABSTRACT:
The alcoholic extract of 85 Malaysian higher plants belonging to 31 different families was assayed for antimicrobial activity against 12 bacteria, 3 fungi, 6 candida/yeast.and one flagillat. The evaluation tests for the antimicrobial activities were performed using the filter paper disc diffusion and tube dilution assays. Solan urn nigrum (Soianaceae), Lawsonia inermis (Lecythidaceae), Phyllenthus niruri (Euphorbiaceae ), and Spondias duicis (Anacardiaceae ) extracts exhibited strong antimicrobial activities againt the tested microorganisms. However, L. inermis extract displayed strong antifungal activity against Aspergillus niger and Cunninghamelia elegans.. Six other extracts showed moderate antimicrobial activities as compared to streptomycin and nystatin standard antibiotics .
- ESSENTIAL OILS OF Thuja occidental is. Thuja orien talis, Cupressus sempervirens, and Juniper us phoenicea
كلية الصيدلة - جامعة المنصورة, الصفحات 37-46, 20/1/1992
أ.د. محمد صفوت عطا عبد المعز عفيفى
أ.د. صالح حسن صالح الشرقاوى
أ.د. جلال طه معتوق عبد الحى
محمود السحيلى - معهد البحوث للعلوم الصيدلية - جامعة المسيسيبى
جاك روذاذا - قسم النواتج الطبيعية والكيمياء الطبية -كلية الصيدلة - جامعة ايوا
الملخص الملخص ESSENTIAL OILS OF Thuja occidental is. Thuja orien talis, Cupressus sempervirens, and Juniper us phoenicea Essential oils were obtained by steam distillation from the twigs and berries of Thuja occidentalis (0.25 and 0.5% w/w, respectively), TilUjp. jjtientalis (0.32 and 0.25%,w/w), Cupressus sempervirens(0.4 and 0.16 W/w), and Juniperusphoenicea(0J5 and 1.25% w/w). Comparisons of the four essential oils were made by gas chromatography/mass spectral (GC7M5) analyses. Major constituents of the oils were o^-thujene, (+)-sabinene^c- and B-pinenes, (+)-camphene, cedrol and cedrenol.
- Iridoid Glycosides from Veronica Montana
Second Anglo-Egyptian Conference of Pharmaceutical Sciences,Alex.
M.-F. Lahloub
AMER M.M.A.
أ.د. صالح حسن صالح الشرقاوى
- Metabolism of T-2 Toxin by Mucor and Asperigllus Sp
Alex. J. Pharm. Sci. (1991) 5 (2), الصفحات 165-171
أ.د. صالح حسن صالح الشرقاوى
AMER M.M.A.
M.-F. Lahloub
د. حامد عباس
- (+)-(Z)-Lanceol acetate from Toriis arvensis
Phytochemistry 37, 473, 1994
Saad, H-E. A., El-Sharkawy, S. H., Rosazza, J. P. and Halim, A. F.
H-E. A. SAAD
أ.د. صالح حسن صالح الشرقاوى
أ.د. احمد فؤاد احمد ابراهيم حليم
الملخص الملخص (+)-(Z)-Lanceol acetate from Toriis arvensis A new bisabolane sesquiterpene ester, (+)- (Z)- lanceol acetate, was isolated from the fruit essential oil of Torilis arvensis. The structure of the new compound was established by spectroscopic methods including 2D NMR (HMQC, HMBC). The E stereoisomer was also detected and identified through GC-MS.
المرفقات
- Biological Activities of Pyrrolidinoindoline Alkaloids From Calycodendron milnei
Planta Med. 61, 313, 1995
H-E. A. SAAD
أ.د. صالح حسن صالح الشرقاوى
Saad, H-E. A., El-Sharkawy, S. H. and Shier, W. T.
الملخص الملخص Biological Activities of Pyrrolidinoindoline Alkaloids From Calycodendron milnei Certain genera of the tribe Psychotrieae, specifically Calycodendron and Psychotria, found on Pacific Islands, synthesize a series of Nb-methyltryptamine-derived alkaloids made up of 2 to 8 pyrrolidinoindoline units. Nine alkaloids of this class have been isolated from the aerial parts and stem bark of Calycodendron milnei, a species endemic to the Vaté Islands (New Hebrides), and examined for potential application as anti-cancer and anti-infective agents. All members of the series exhibited readily detected cytotoxic activity against proliferating and non-proliferating Vero African green monkey kidney cells in culture, with the most potent activity being exhibited by vatamine and quadrigemine C. Only hodgkinsine A exhibited substantial antiviral activity against a DNA virus, Herpes simplex type 1, and an RNA virus, Vesicular stomatitis virus. All members of the series showed readily detected anti-bacterial, anti-fungal and anti-candidal activities using both tube dilution and disc diffusion assay methods. The most potent anti-microbial alkaloids were hodgkinsine A and quadrigemine C, which exhibited minimum inhibitory concentration (MIC) values as low as 5 µg/ml.
- Composition of the Essential Oils of the Leaves and Stems of Torilis arvensis
Pharm. Acta Helv. 70, 85, 1995.
Saad, H-E. A., El-Sharkawy, S. H. and Halim, A. F.
H-E. A. SAAD
أ.د. صالح حسن صالح الشرقاوى
أ.د. احمد فؤاد احمد ابراهيم حليم
الملخص الملخص Composition of the Essential Oils of the Leaves and Stems of Torilis arvensis The leaf and stem essential oils of Torilis arvensis were obtained by hydrodistillation (0.26% & 0.16%) and analyzed by GC-MS. The oils consist of at least 39 (leaves) and 34 (stems) components 25 and 22 of which, accounting for about 86% and 77% respectively of the oils composition, were identified. Both oils are dominated by trans-*-farnesene and containing significant amounts of *-cubebene, cis-*-farnesene, *-caryophyllene and nuciferyl acetate. The new and major sesquiterpene ester, (+)-(Z)-lanceol acetate, of the fruit essential oil was totally absent from both oils.
المرفقات
- Essential Oils of Daucus carota ssp. Maximus
Pharm. Acta Helv. 70, 79, 1995
Saad, H-E. A., El-Sharkawy, S. H. and Halim, A. F.
H-E. A. SAAD
أ.د. صالح حسن صالح الشرقاوى
أ.د. احمد فؤاد احمد ابراهيم حليم
الملخص الملخص Essential Oils of Daucus carota ssp. Maximus The fruit, leaf and stem essential oils of Daucus carota ssp. maximus have been studied by GC-MS. The fruit oil consists chiefly of phenylpropanoids and sesquiterpene hydrocarbons. It is characterized by the presence of trans-methylisoeugenol, methyl-eugenol, *-asarone, shyobunone and preisocalamendiol. Phenylpropanoids are completely absent from both the leaf and stem oils and the oxygenated sesquiterpenes constitute about 52 and 80%, respectively of the oils composition, with shyobunones and preisocalamendiol as major component. These monocyclic ketones as well as *-bourbonene, aristol-9-en-3-ol and aristolenol have never before been reported as components of any Daucus oil. Unlike most of the studied varieties, carotol, daucol and geranyl acetate are completely absent. These results reflect the unique composition of the essential oils of this Lebanese variety.
المرفقات
- Microbial Reduction of Carvone and Citral, Two ?, ?-Unsaturated Carbonyl Monoterpenes
As-Pac. J. Mol. Biol. Biotechnol. 2, 33, 1994
El-Sharkawy, S. H. and Saad, H-E. A.
H-E. A. SAAD
أ.د. صالح حسن صالح الشرقاوى
الملخص الملخص Microbial Reduction of Carvone and Citral, Two ?, ?-Unsaturated Carbonyl Monoterpenes R-(-)-Carvone has been transformed by Hansenula anomale ATCC 20144 into three pure metabolites, dihydrocarveol, 1, 2R, 4R, 7R (+)-2,7-Oxidomenthan-8-ol, 2, and p-menth-8-en-3-ol, 3, in 19.2%, 25%, and 22.5% yield, respectively. Sacchromyces cervisiae UI-Sacch converted citral into two metabolites, 3,7-dimethyl-2,6-octadiene-1-ol, 4, and 3,7-dimethyl-6-octene-1-ol, 5, in 10% and 54% yield, respectively. Three types of reactions were observed namely, epoxidation and hydration of the double bond as well as reduction of the carbonyl. The identity of the isolated metabolites was established using IR, MS, as well as both 1H- and 13C-NMR (1D- and 2D) spectroscopy.
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6-(+)-(Z)-Lanceol acetate from Torilis arvensis.pdf